Her nationality is American and belongs to mixed (Filipino, Italian, Irish, and Ashkenazi Jewish) ethnicity. She is the daughter of Vincent Charles Minnillo and Helen Ramos Bercero.
Her father is an American citizen from Cleveland, Ohio of Italian and Irish descent.
She was a host on MTV's Total Request Live (TRL) from 2003 until 2007 and became a New York City correspondent for Entertainment Tonight in 2005.
Minnillo hosted Miss Teen USA (2004) and co-hosted Miss Universe (2007).
In 2008, she played Ashlee in the How I Met Your Mother episode "No Tomorrow".
She starred in the 2008 comedy Disaster Movie, a spoof of big-budget Hollywood disaster movies.
Released on August 29, 2008, the film had moderate box office success, earning ,624,652 worldwide.
The film received extremely negative reviews, earning six Razzie Award nominations.
Her father moved the family frequently because of his service in the Air Force. relocated to Turkey with their mother and new stepfather.As of January 2011, it stands at number sixteen on the IMDb Bottom 100.Lachey (called Minnillo back then) signed on to appear in Redefining Love, a 2009 romantic comedy, In November 2009, announced that Minnillo would guest star alongside Disaster Movie co-star Kim Kardashian on CBS's CSI: NY.Minnillo later guest starred on the then-new series Hawaii Five-0 with then fiancé Nick Lachey.On September 6, 2017, Lachey was announced as one of the celebrities who will take part on the 25th season of Dancing with the Stars, competing against her husband Nick.